Sunday, January 31, 2010
Where are they now?
Steven is the first student to receive his Master's Degree through the UMBTC. His award winning research showed that knocking down the enzyme MGMT using a technique called RNA interference (RNAi) can make brain cancer cells more sensitive to chemotherapy. MGMT is a normal enzyme that repairs DNA damage, so it is very important in keeping our cells healthy. Most chemotherapy works by damaging DNA. So if cancer cells have active DNA repair mechanisms, the DNA damage caused by chemotherapy is fixed, thus thwarting the destruction of the cancer cell. By using (RNAi), Steven showed that the levels of MGMT in a malignant glioma cell can be reduced and that cell becomes more sensitive to temozolomide (Temodar) chemotherapy.
Steven set the bar high for the next generation of graduate students.
Congratulations, and good luck in your future endeavors.